Colchicine Lowers the Risk of Atrial Fibrillation (AF)

November 23, 2011 by Estella .

Colchicine, an oral anti-gout agent has been used for centuries for the treatment of gout; it was approved in the US in 2007. It is also used to treat familial Mediterranean fever (FMF).

In the latest study from COPPS (Colchicine for the Prevention of the Postpericardiotomy Syndrome), Colchicine therapy could become a safe and inexpensive way to prevent post-surgery of atrial fibrillation. The result showed patients on Colchicine had a significantly reduced incidence of postoperative AF between days 3 and 30, with a relative risk reduction of 45.5%, compared with those taking placebo (p=0.021). Colchicine use was also associated with a shorter in-hospital stay.

However, Dr Nancy Nussmeier (SUNY Upstate Medical University, Syracuse, NY), anesthesiologist, told heartwires: I don't recommend the routine use of colchicine for the prevention of postoperative AF on the basis of a single trial. We need further multicenter trials to confirm this. Read the full article, >Click here<.

Filed under: Atrial Fibrillation.

Tags: colchicine, colchicine for gout, gout medication, gout drug, anti-inflammatory, risks of atrial fibrillation, post-op, postoperative atrial fibrillation.

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